2024-04-09
The Regulatory Role of Matrix Proteins in Mineralization of Bone
d.3. Bone Acidic Glycoprotein-75 and Dentin Matrix Protein-1Another sialoprotein originally isolated from rat bone has an apparent molecular weight of ∼75 kDa and hence is called bone acidic glycoprotein-75 (BAG-75) [424–426]. This protein is heavily glycosylated and contains 7% sialic acid and 8% phosphate. Thirty percent of the residues in this protein are acidic in nature.